12 Best Fall Mezcal Cocktails to Drink

The Smoky Harvest Apple Cider Margarita is a fall-inspired cocktail that combines the bold character of mezcal with the sweet, crisp taste of apple cider. The smoky notes of mezcal add depth and warmth, while the cider brings refreshing fruitiness that ties the drink to the season.

A touch of cinnamon and nutmeg enhances the flavor with comforting spice, giving each sip a cozy finish. Served over ice with an optional spiced rim, this margarita is perfect for apple-picking days, festive gatherings, or nights by the fire. It is a balanced drink that highlights the best flavors of autumn.

The Mezcal Negroni is a bold variation of the classic cocktail, bringing smoky depth to a drink known for its balance of bittersweet flavors. Traditional Negronis are made with gin, but substituting mezcal adds an earthy, smoky character that pairs beautifully with sweet vermouth and bitter liqueur.

The result is a complex drink that feels both familiar and fresh, offering layers of flavor that linger with each sip. Its rich amber color and aromatic profile make it as striking in appearance as it is in taste. Perfect for autumn evenings or gatherings with friends, it’s a true seasonal favorite.

The Apple Cider Mezcal Margarita is a seasonal twist on a classic cocktail, combining smoky flavor with crisp autumn sweetness. Mezcal brings an earthy depth that pairs beautifully with the fresh, fruity taste of apple cider.

Lime juice adds brightness, while a touch of cinnamon sugar on the rim gives the drink extra warmth and a festive finish. Served over ice, it is both refreshing and comforting, making it an excellent choice for fall parties, Thanksgiving dinners, or casual evenings with friends. This margarita blends familiar flavors with a smoky edge, creating a drink that feels perfect for the season.

The Smoky & Spicy Orange Cocktail is a bold drink that highlights the balance of citrus, smoke, and gentle heat. Mezcal provides a rich smoky base, while orange liqueur adds sweetness and brightness that keeps the flavor lively.

A chili-infused syrup gives the cocktail a subtle warmth, adding just enough spice to make each sip interesting without overpowering the other ingredients. Served over ice, it can be garnished with a slice of orange or a chili pepper for extra color and aroma. This cocktail is a great choice for fall gatherings, dinner parties, or evenings when you want something unique.

The Mezcal Mule is a smoky variation of the classic Moscow Mule, bringing an earthy depth that sets it apart from the original. Mezcal serves as the base, offering a bold and smoky flavor that blends seamlessly with the tang of fresh lime juice.

Ginger beer adds fizz and spice, creating a lively balance that keeps the drink refreshing while still full of character. Traditionally served in a copper mug and garnished with lime and mint, the Mezcal Mule looks just as inviting as it tastes. It’s an excellent choice for autumn evenings, casual gatherings, or sharing with friends.

The Lime Basil Mezcalita is a refreshing cocktail that blends smoky depth with bright herbal notes. Mezcal gives the drink its bold and earthy flavor, while fresh lime juice adds tang and balance. Basil leaves bring a fragrant, herbal freshness that pairs beautifully with the smokiness, creating a cocktail that feels light yet full of character.

A touch of sweetness helps round out the flavors, making each sip smooth and enjoyable. Served over ice and garnished with basil and lime, it is perfect for relaxed evenings, outdoor gatherings, or any occasion where a flavorful and memorable drink is welcome.

The Smoky Autumn Mezcal Spritz is a refreshing cocktail that balances the bold, earthy flavor of mezcal with the light fizz of sparkling water. The smokiness of the mezcal gives the drink depth, while the bubbles keep it crisp and easy to sip.

Citrus juice or a splash of liqueur can be added to brighten the flavors, making the spritz smooth yet lively. Garnished with fresh herbs or a slice of orange, it looks as inviting as it tastes. Perfect for fall brunches, relaxed afternoons, or festive gatherings, this spritz offers a seasonal twist on a classic mezcal drink.

The Blood Orange Mezcalita is a bold and colorful cocktail that highlights the balance of smoky and citrus flavors. Mezcal provides its signature earthy depth, while fresh blood orange juice adds natural sweetness and a striking ruby hue.

Lime juice brightens the drink with tangy freshness, creating a lively mix that feels both smooth and refreshing. Served over ice with a salted or spiced rim, it looks just as inviting as it tastes. Perfect for gatherings, celebrations, or relaxed evenings, this mezcalita is a seasonal favorite that combines smoky warmth with the crisp, juicy flavor of blood oranges.

The Spicy Mezcal Sour is a bold cocktail that combines smoky depth with fiery heat and a refreshing citrus edge. Mezcal gives the drink its earthy, smoky base, while fresh lime juice adds brightness and tang.

A touch of sweetness helps balance the flavors, and the addition of chili or jalapeño brings a gentle burn that lingers pleasantly on the palate. Shaken with ice until smooth and topped with a frothy finish, this cocktail is both warming and refreshing. Perfect for cozy evenings, small gatherings, or whenever you want a drink with character, it’s a flavorful twist on the classic sour.

The Fall Margarita is a seasonal twist on a classic cocktail, blending smoky mezcal with bright citrus and natural sweetness. Fresh lime juice gives the drink a crisp and tangy flavor, while agave syrup smooths out the edges with gentle sweetness.

The mezcal adds depth and smokiness, making this margarita feel warm and full of character, perfect for autumn gatherings. Served over ice with a salted or spiced rim, it is as inviting to look at as it is to sip. Whether enjoyed on the patio, during happy hour, or at a festive dinner, this cocktail fits the fall season.

The Clementine Mezcal Margarita is a refreshing take on the classic margarita, perfect for anyone who loves citrus flavor. Fresh clementine juice gives the drink a bright, tangy sweetness that pairs beautifully with the smoky character of mezcal. Lime juice adds an extra layer of citrus sharpness, while agave syrup smooths the flavors with gentle sweetness.

Served over ice with a salted or spiced rim, it is as eye-catching as it is flavorful. Garnished with clementine wedges or lime slices, this cocktail is ideal for fall picnics, family gatherings, or relaxed evenings when you want a seasonal margarita with flair.